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Object[Protocol, CapillaryGelElectrophoresisSDS]

A protocol for performing a Capillary gel Electrophoresis-Sodium Dodecyl Sulfate (CESDS) experiment on samples to separate denatured proteins according to their molecular weight by electrophoresis through a sieving matrix.

Organizational Information

    Name

    Name of this Object.
    Format: Single
    Class: String
    Programmatic Pattern: _String
    Pattern Description: A string.

    ID

    ID of this Object.
    Format: Single
    Class: String
    Programmatic Pattern: _String
    Pattern Description: The ID of this object.

    Object

    Object of this Object.
    Format: Single
    Class: Expression
    Programmatic Pattern: Object[Protocol, CapillaryGelElectrophoresisSDS, _String]
    Pattern Description: The object reference of this object.

    Type

    Type of this Object.
    Format: Single
    Class: Expression

    Notebook

    Notebook this object belongs to.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link
    Pattern Description: An object of that matches ObjectP[Object[LaboratoryNotebook]].

    Author

    The investigator who created this protocol.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

General

    DateConfirmed

    The date on which the protocol first entered processing or a backlog.
    Format: Single
    Class: Date
    Programmatic Pattern: _?DateObjectQ

    DateEnqueued

    The date on which the protocol was accepted and added to the queue.
    Format: Single
    Class: Date
    Programmatic Pattern: _?DateObjectQ

    DateStarted

    The date on which the protocol moved from the front of the queue to begin running in the lab.
    Format: Single
    Class: Date
    Programmatic Pattern: _?DateObjectQ

    DateCompleted

    The date on which the last step of this protocol's execution was finished.
    Format: Single
    Class: Date
    Programmatic Pattern: _?DateObjectQ

    DateCanceled

    The date on which the protocol was canceled and removed from the queue.
    Format: Single
    Class: Date
    Programmatic Pattern: _?DateObjectQ

    Script

    The script that created this protocol.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    SubprotocolScripts

    All scripts generated by this protocol as a list of subprotocols.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    Site

    The ECL site at which this protocol was executed.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    SamplesIn

    Input samples for this analytical or preparative experiment.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    ContainersIn

    Any containers containing this protocols' SamplesIn.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    NumberOfReplicates

    Indicates the number of times the experiment is repeated with identical parameters.
    Format: Single
    Class: Integer
    Programmatic Pattern: GreaterP[0, 1]

    Status

    The current status of the protocol.
    Format: Single
    Class: Expression
    Programmatic Pattern: ProtocolStatusP

    CheckpointProgress

    A listing of all the checkpoints passed in the execution of this protocol.
    Format: Multiple

    [[1]] Name

      Header: Name
      Class: String
      Programmatic Pattern: _String

    [[2]] Start Time

      Header: Start Time
      Class: Date
      Programmatic Pattern: _?DateObjectQ

    [[3]] End Time

      Header: End Time
      Class: Date
      Programmatic Pattern: _?DateObjectQ|Null

    SubprotocolDescription

    A short title indicating what this subprotocol accomplishes.
    Format: Single
    Class: String
    Programmatic Pattern: _String

    BatchedUnitOperations

    The individual batches of the protocol, as they will be executed in the lab.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    ReplacementProtocol

    If this protocol was aborted due to technical reasons, links to the replacement protocol run in its place.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    Sterile

    Indicates if the protocol is performed in a sterile environment.
    Format: Single
    Class: Expression
    Programmatic Pattern: BooleanP

    LiquidHandlingLog

    The instrumentation trace file that monitored and recorded the execution of this robotic liquid handling.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    PooledSamplesIn

    The members of SamplesIn gathered into the pools that are mixed in each AliquotContainer.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: {ObjectReferenceP[Object[Sample]]..}

    NestedIndexMatchingSamplesIn

    The members of SamplesIn gathered into the pools that are mixed in each AliquotContainer.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: {ObjectReferenceP[Object[Sample]]..}

    InitialNitrogenPressure

    The pressure data of the nitrogen gas source before starting the experiment.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    NitrogenPressureLog

    The pressure log for the nitrogen gas source for the relevant section of the facility.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    InitialCO2Pressure

    The pressure data of the CO2 gas source before starting the experiment.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    CO2PressureLog

    The pressure log for the CO2 gas source for the relevant section of the facility.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    InitialArgonPressure

    The pressure data of the argon gas source before starting the experiment.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    HoldOrder

    Indicates if the queue position of this protocol should be strictly enforced, regardless of the available resources in the lab.
    Format: Single
    Class: Boolean
    Programmatic Pattern: BooleanP

    Priority

    Indicates if this protocol should be prioritized to start at the given StartDate, have dedicated operation for its entirety, and not be interrupted by other protocols.
    Format: Single
    Class: Boolean
    Programmatic Pattern: BooleanP

    StartDate

    The date at which this protocol should be prioritized to start.
    Format: Single
    Class: Date
    Programmatic Pattern: _?DateObjectQ

    Branch

    The git branch that this protocol should be run on.
    Format: Single
    Class: String
    Programmatic Pattern: _String

    Instrument

    The device on which the protocol is run. The instrument is loaded with a cartridge that holds the capillary in which Capillary gel Electrophoresis-Sodium Dodecyl Sulfate (CESDS) is performed as well as the anode running buffer required for this experiment. Samples are first denatured by heating in the presence of SDS, imparting all proteins in the sample a negative charge and a similar charge to mass ratio. For every sample, separation matrix is loaded onto the capillary and the sample is electroinjected into the matrix. Subsequently, a voltage is applied on the capillary and proteins migrate through the sieving matrix where smaller proteins migrate faster than larger ones. Proteins are detected as they migrate past a UV absorbance detector and relative migration times are calculated relative to an internal standard.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    AssayPlate

    The 96-well plate holding all reagents and samples for a Capillary gel Electrophoresis-SDS experiment loaded onto the instrument.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    SamplePreparationPlate

    The 96-well plate in which sample preparation for a Capillary gel Electrophoresis-SDS experiment takes place.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    RunTime

    The total time capillary gel electrophoresis sds is expected to run.
    Format: Single
    Class: Real
    Unit: 1 minute
    Programmatic Pattern: GreaterP[0 Second]

    InjectionTable

    The sequence of injections for a given experiment run for SamplesIn, Ladders, Standards, and Blanks.
    Format: Multiple

    [Type]

      Header: Type
      Class: Expression

    [Sample]

    [Volume]

      Header: Volume
      Class: Real
      Unit: 1 microliter

    [Data]

    [SampleIndex]

      Header: SampleIndex
      Class: Integer

    MethodFile

    The methods file containing the run parameters for all samples in protocol.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    InjectionListFile

    The file specifying the order of sample injection and associated method names for all samples in the protocol.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

Replicate Experiments

    Template

    The protocol whose option selections should be selected as the default options for this protocol.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    ProtocolsTemplated

    Protocols which were generated using this protocol's options as a starting point for its option defaults.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

Sample Preparation

    PreparatoryUnitOperations

    A list of transfers, consolidations, aliquots, mixes and dilutions that will be performed in the order listed to prepare samples for the experiment.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: _ | _

    PreparatoryPrimitives

    A list of transfers, consolidations, aliquots, mixes and dilutions that will be performed in the order listed to prepare samples for the experiment.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: _ | _

    VolumeCheckSamplePrep

    Indicates if any liquid samples prepared by using the PreparatoryUnitOperations option should have their volumes measured and updated before running the experiment.
    Format: Single
    Class: Expression
    Programmatic Pattern: BooleanP

    IncubateSamplePreparation

    For each member of SamplesIn, parameters describing how the input samples should be heated prior to any aliquoting or the start of the experiment.
    Format: Multiple

    [Incubate]

      Header: Incubate
      Class: Boolean

    [IncubationTemperature]

      Header: IncubationTemperature
      Class: Real
      Unit: 1 degree Celsius

    [IncubationTime]

      Header: IncubationTime
      Class: Real
      Unit: 1 second

    [Mix]

      Header: Mix
      Class: Boolean

    [MixType]

      Header: MixType
      Class: Expression

    [MixUntilDissolved]

      Header: MixUntilDissolved
      Class: Boolean

    [MaxIncubationTime]

      Header: MaxIncubationTime
      Class: Real
      Unit: 1 second

    [IncubationInstrument]

    [AnnealingTime]

      Header: AnnealingTime
      Class: Real
      Unit: 1 second

    [IncubateAliquotContainer]

      Header: IncubateAliquotContainer
      Class: Expression

    [IncubateAliquot]

      Header: IncubateAliquot
      Class: Real
      Unit: 1 liter

    [IncubateAliquotDestinationWell]

      Header: IncubateAliquotDestinationWell
      Class: Expression

    CentrifugeSamplePreparation

    For each member of SamplesIn, parameters describing how the input samples should be spun down prior to any aliquoting or the start of the experiment.
    Format: Multiple

    [Centrifuge]

      Header: Centrifuge
      Class: Boolean

    [CentrifugeInstrument]

    [CentrifugeIntensity]

      Header: CentrifugeIntensity
      Class: VariableUnit

    [CentrifugeTime]

      Header: CentrifugeTime
      Class: Real
      Unit: 1 minute

    [CentrifugeTemperature]

      Header: CentrifugeTemperature
      Class: Real
      Unit: 1 degree Celsius

    [CentrifugeAliquotContainer]

      Header: CentrifugeAliquotContainer
      Class: Expression

    [CentrifugeAliquot]

      Header: CentrifugeAliquot
      Class: Real
      Unit: 1 liter

    [CentrifugeAliquotDestinationWell]

      Header: CentrifugeAliquotDestinationWell
      Class: Expression

    FilterSamplePreparation

    For each member of SamplesIn, parameters describing how particulates should be separated from the input samples prior to any aliquoting or the start of the experiment.
    Format: Multiple

    [Filtration]

      Header: Filtration
      Class: Boolean

    [FiltrationType]

      Header: FiltrationType
      Class: Expression

    [Filter]

    [FilterMaterial]

      Header: FilterMaterial
      Class: Expression

    [FilterPoreSize]

      Header: FilterPoreSize
      Class: Real
      Unit: 1 micrometer

    [FilterContainerOut]

      Header: FilterContainerOut
      Class: Expression

    [FilterInstrument]

    [FilterSyringe]

    [FilterHousing]

    [FilterIntensity]

      Header: FilterIntensity
      Class: VariableUnit

    [FilterTime]

      Header: FilterTime
      Class: Real
      Unit: 1 minute

    [FilterTemperature]

      Header: FilterTemperature
      Class: Real
      Unit: 1 degree Celsius

    [FilterSterile]

      Header: FilterSterile
      Class: Boolean

    [FilterAliquotContainer]

      Header: FilterAliquotContainer
      Class: Expression

    [FilterAliquot]

      Header: FilterAliquot
      Class: Real
      Unit: 1 liter

    [PrefilterMaterial]

      Header: PrefilterMaterial
      Class: Expression

    [PrefilterPoreSize]

      Header: PrefilterPoreSize
      Class: Real
      Unit: 1 micrometer

    [FilterAliquotDestinationWell]

      Header: FilterAliquotDestinationWell
      Class: Expression

    SamplePreparationProtocols

    Protocols used to mix, centrifuge, incubate, and filter the SamplesIn prior to starting the experiment.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    PooledIncubateSample Preparation

    For each member of PooledSamplesIn, parameters describing how the pooled samples should be incubated after aliquoting but prior to the start of the experiment.
    Format: Multiple

    [Incubate]

      Header: Incubate
      Class: Boolean

    [IncubationTemperature]

      Header: IncubationTemperature
      Class: Real
      Unit: 1 degree Celsius

    [IncubationTime]

      Header: IncubationTime
      Class: Real
      Unit: 1 second

    [Mix]

      Header: Mix
      Class: Boolean

    [MixType]

      Header: MixType
      Class: Expression

    [MixUntilDissolved]

      Header: MixUntilDissolved
      Class: Boolean

    [MaxIncubationTime]

      Header: MaxIncubationTime
      Class: Real
      Unit: 1 second

    [IncubationInstrument]

    [AnnealingTime]

      Header: AnnealingTime
      Class: Real
      Unit: 1 second

    [IncubateAliquotContainer]

      Header: IncubateAliquotContainer
      Class: Expression

    [IncubateAliquot]

      Header: IncubateAliquot
      Class: Real
      Unit: 1 liter

    [IncubateAliquotDestinationWell]

      Header: IncubateAliquotDestinationWell
      Class: Expression

    NestedIndexMatchingIncubate SamplePreparation

    For each member of NestedIndexMatchingSamplesIn, parameters describing how the pooled samples should be incubated after aliquoting but prior to the start of the experiment.
    Format: Multiple

    [Incubate]

      Header: Incubate
      Class: Boolean

    [IncubationTemperature]

      Header: IncubationTemperature
      Class: Real
      Unit: 1 degree Celsius

    [IncubationTime]

      Header: IncubationTime
      Class: Real
      Unit: 1 second

    [Mix]

      Header: Mix
      Class: Boolean

    [MixType]

      Header: MixType
      Class: Expression

    [MixUntilDissolved]

      Header: MixUntilDissolved
      Class: Boolean

    [MaxIncubationTime]

      Header: MaxIncubationTime
      Class: Real
      Unit: 1 second

    [IncubationInstrument]

    [AnnealingTime]

      Header: AnnealingTime
      Class: Real
      Unit: 1 second

    [IncubateAliquotContainer]

      Header: IncubateAliquotContainer
      Class: Expression

    [IncubateAliquot]

      Header: IncubateAliquot
      Class: Real
      Unit: 1 liter

    [IncubateAliquotDestinationWell]

      Header: IncubateAliquotDestinationWell
      Class: Expression

    PooledCentrifugeSample Preparation

    For each member of PooledSamplesIn, parameters describing how the pooled samples should be centrifuge after aliquoting and pooled mixing but prior to the start of the experiment.
    Format: Multiple

    [Centrifuge]

      Header: Centrifuge
      Class: Boolean

    [CentrifugeInstrument]

    [CentrifugeIntensity]

      Header: CentrifugeIntensity
      Class: VariableUnit

    [CentrifugeTime]

      Header: CentrifugeTime
      Class: Real
      Unit: 1 minute

    [CentrifugeTemperature]

      Header: CentrifugeTemperature
      Class: Real
      Unit: 1 degree Celsius

    [CentrifugeAliquotContainer]

      Header: CentrifugeAliquotContainer
      Class: Expression

    [CentrifugeAliquot]

      Header: CentrifugeAliquot
      Class: Real
      Unit: 1 liter

    [CentrifugeAliquotDestinationWell]

      Header: CentrifugeAliquotDestinationWell
      Class: Expression

    NestedIndexMatchingCentrifuge SamplePreparation

    For each member of PooledSamplesIn, parameters describing how the pooled samples should be centrifuge after aliquoting and pooled mixing but prior to the start of the experiment.
    Format: Multiple

    [Centrifuge]

      Header: Centrifuge
      Class: Boolean

    [CentrifugeInstrument]

    [CentrifugeIntensity]

      Header: CentrifugeIntensity
      Class: VariableUnit

    [CentrifugeTime]

      Header: CentrifugeTime
      Class: Real
      Unit: 1 minute

    [CentrifugeTemperature]

      Header: CentrifugeTemperature
      Class: Real
      Unit: 1 degree Celsius

    [CentrifugeAliquotContainer]

      Header: CentrifugeAliquotContainer
      Class: Expression

    [CentrifugeAliquot]

      Header: CentrifugeAliquot
      Class: Real
      Unit: 1 liter

    [CentrifugeAliquotDestinationWell]

      Header: CentrifugeAliquotDestinationWell
      Class: Expression

    FilteredSamples

    Samples corresponding to filtered eluents of SamplesIn generated during sample preparation and intended for use in this experiment.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link
    Relation: Object[Sample]

    Denature

    Indicates if heat denaturation should be applied to all samples.
    Format: Single
    Class: Boolean
    Programmatic Pattern: BooleanP

    DenaturingTemperature

    Indicates the temperature to which samples will be heated in order to linearize proteins in the sample.
    Format: Single
    Class: Real
    Unit: 1 degree Celsius
    Programmatic Pattern: GreaterP[0 Kelvin]

    DenaturingTime

    Indicates the duration samples will be incubated at the DenaturingTemperature.
    Format: Single
    Class: Real
    Unit: 1 minute
    Programmatic Pattern: GreaterP[0 Second]

    CoolingTemperature

    Indicates the temperature at which samples will be cooled after denaturation.
    Format: Single
    Class: Real
    Unit: 1 degree Celsius
    Programmatic Pattern: GreaterP[0 Kelvin]

    CoolingTime

    Indicates the duration samples will be incubated at the CoolingTemperatures.
    Format: Single
    Class: Real
    Unit: 1 minute
    Programmatic Pattern: GreaterP[0 Second]

    PelletSedimentation

    Indicates if centrifugation should be applied to the sample to remove precipitates after denaturation.
    Format: Single
    Class: Boolean
    Programmatic Pattern: BooleanP

    SedimentationCentrifugation Speed

    Indicates the speed of centrifugation applied to remove precipitates.
    Format: Single
    Class: Integer
    Unit: 1 revolution per minute
    Programmatic Pattern: GreaterP[0 RPM]

    SedimentationCentrifugation Force

    Indicates the force of centrifugation applied to remove precipitates.
    Format: Single
    Class: Integer
    Unit: 1 standard acceleration due to gravity on the surface of the earth
    Programmatic Pattern: GreaterP[0 GravitationalAcceleration]

    SedimentationCentrifugation Time

    Indicates the duration samples will be centrifuged to remove precipitates.
    Format: Single
    Class: Real
    Unit: 1 minute
    Programmatic Pattern: GreaterP[0 Second]

    SedimentationCentrifugation Temperature

    Indicates the temperature at which samples will be held while centrifugating to remove precipitates.
    Format: Single
    Class: Real
    Unit: 1 degree Celsius
    Programmatic Pattern: GreaterP[0 Kelvin]

    AssayContainers

    The containers the samples are assayed in.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    TotalVolumes

    For each member of SamplesIn, indicates the final volume in the assay tube prior to loading onto AssayContainer. Each tube contains Sample, InternalReference, SDSBuffer, and ReducingAgent and/or AlkylatingAgent.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    SampleVolumes

    For each member of SamplesIn, indicates the volume of sample required.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    PremadeMasterMixReagents

    For each member of SamplesIn, indicates the premade master mix used for CESDS experiment, containing an SDS buffer, an internal standard, and reducing and / or alkylating agents (if applicable).
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    PremadeMasterMixDiluents

    For each member of SamplesIn,indicates the solution used to dilute the premade master mix used to its working concentration.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    PremadeMasterMixReagent DilutionFactors

    For each member of SamplesIn, indicates the factor by which the premade mastermix should be diluted by in the final assay tube.
    Format: Multiple
    Class: Real
    Programmatic Pattern: GreaterP[1]

    PremadeMasterMixVolumes

    For each member of SamplesIn, indicates the volume of the premade mastermix required to reach its final concentration.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    InternalReferences

    For each member of SamplesIn, indicates the internal standard stock solution added in sample preparation. The internal standard stock solution contains the analyte that serves as the reference by which Relative Migration Time is normalized. By default a 10 KDa marker is used.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    InternalReferenceDilution Factors

    For each member of SamplesIn, indicates the factor by which the InternalReference needs to be diluted to reach working concentration.
    Format: Multiple
    Class: Real
    Programmatic Pattern: GreaterP[1]

    InternalReferenceVolumes

    For each member of SamplesIn, indicates the volume of InternalReference to be diluted by a factor equal to InternalReferenceDilutionFactor to reach working concentration in the final assay volume containing all other components (i.e., sample, SDS buffer, and reducing/alkylating agents).
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    ConcentratedSDSBuffers

    For each member of SamplesIn, indicates the SDS Buffer concentrate used to dilute and denature the sample.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    ConcentratedSDSBufferDilution Factors

    For each member of SamplesIn, indicates the factor by which the ConcentratedSDSBuffer needs to be diluted to reach working concentration.
    Format: Multiple
    Class: Real
    Programmatic Pattern: GreaterEqualP[1]

    ConcentratedSDSBufferVolumes

    For each member of SamplesIn, indicates the volume of ConcentratedSDSBuffer to reach its working concentration in the final assay volume containing all other components (i.e., sample, internal standard, and reducing/alkylating agents).
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    Diluents

    For each member of SamplesIn, indicates the solution used to bring the assay tube to TotalVolume so that all components are at working concentration in the final assay volume containing all other components (i.e., sample, internal standard, SDS buffer, and reducing/alkylating agents).
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    SDSBuffers

    For each member of SamplesIn, indicates the SDS Buffer used to dilute and denature the sample.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    SDSBufferVolumes

    For each member of SamplesIn, indicates the volume of SDSBuffer to add to sample to reach working concentration in the final assay volume containing all other components (i.e., sample, internal standard, and reducing/alkylating agents).
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    ReducingAgents

    For each member of SamplesIn, indicates the reducing agent, e.g., β-mercaptoethanol or Dithiothreitol, added to the sample to reduce disulfide bridges in proteins.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    ReducingAgentTarget Concentrations

    For each member of SamplesIn, indicates the final concentration of the ReducingAgent in the sample.
    Format: Multiple
    Class: VariableUnit
    Programmatic Pattern: GreaterEqualP[0 Molar] | RangeP[0 VolumePercent, 100 VolumePercent]

    ReducingAgentVolumes

    For each member of SamplesIn, indicates the volume of the ReducingAgent added to the sample to reach working concentration in the final assay volume containing all other components (i.e., sample, internal standard, SDSBuffer and alkylating agents).
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    AlkylatingAgents

    For each member of SamplesIn, indicates the alkylating agent, e.g., Iodoacetamide, added to the sample to prevent protein fragmentation.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    AlkylatingAgentTarget Concentrations

    For each member of SamplesIn, indicates the final concentration of the AlkylatingAgent in the sample.
    Format: Multiple
    Class: Real
    Unit: 1 millimolar
    Programmatic Pattern: GreaterEqualP[0 Molar]

    AlkylatingAgentVolumes

    For each member of SamplesIn, indicates the volume of the AlkylatingAgent added the sample.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    SedimentationSupernatant Volumes

    For each member of SamplesIn, indicates the volume of supernatant that should be aliquoted to assay AssayContainer after denaturation and centrifugation.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    InternalReferenceStorage Conditions

    For each member of SamplesIn, indicates the non-default storage condition for the InternalReference after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    ConcentratedSDSBufferStorage Conditions

    For each member of SamplesIn, indicates the non-default storage condition for the ConcentratedSDSBuffer after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    DiluentStorageConditions

    For each member of SamplesIn, indicates the non-default storage condition for the Diluent after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    SDSBufferStorageConditions

    For each member of SamplesIn, indicates the non-default storage condition for the SDSBuffer after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    ReducingAgentStorage Conditions

    For each member of SamplesIn, indicates the non-default storage condition for the ReducingAgent after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    AlkylatingAgentStorage Conditions

    For each member of SamplesIn, indicates the non-default storage condition for the AlkylatingAgent after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    SamplePreparationPrimitives

    A set of instructions specifying the preparation of samples, ladders, standards, and blanks for capillary gel Electrophoresis SDS experiments, including dilution in SDS buffer, spiking internal standards, and addition of any reducing and / or alkylating agents.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleManipulationP

    SamplePreparationProtocol

    The sample manipulation protocol used to prepare samples for capillary gel Electrophoresis SDS experiments.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    PostIncubationTransferSM Primitives

    A set of instructions specifying the transfer of samples, ladders, standards, and blanks from sample preparation plate to assay plate after incubation and centrifugation for capillary gel Electrophoresis SDS experiments.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleManipulationP

    PostIncubationTransferSM Protocol

    The sample manipulation protocol used to transfer of samples, ladders, standards, and blanks from sample preparation plate to assay plate after incubation and centrifugation for capillary gel Electrophoresis SDS experiments.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    IncubationProtocol

    The PCR protocol used to heat denature samples, ladders, Standards, and Blanks for capillary ELISA experiments.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    CentrifugationProtocol

    The centrifugation protocol used to remove any precipitates after denaturation in preparation for capillary gel Electrophoresis SDS experiments.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

Aliquoting

    AliquotSamplePreparation

    For each member of AliquotSamples, parameters describing how aliquots should be drawn from the input samples after initial sample preparation in order to create new aliquot samples upon which aliquot preparation and the experiment should proceed.
    Format: Multiple

    [Aliquot]

      Header: Aliquot
      Class: Boolean

    [AliquotAmount]

      Header: AliquotAmount
      Class: Expression

    [TargetConcentration]

      Header: TargetConcentration
      Class: Expression

    [AssayVolume]

      Header: AssayVolume
      Class: Real
      Unit: 1 milliliter

    [AliquotContainer]

      Header: AliquotContainer
      Class: Expression

    [AssayBuffer]

    [BufferDiluent]

    [BufferDilutionFactor]

      Header: BufferDilutionFactor
      Class: Real

    [ConcentratedBuffer]

    [DestinationWell]

      Header: DestinationWell
      Class: Expression

    [TargetConcentrationAnalyte]

      Header: TargetConcentrationAnalyte
      Class: Expression

    [AliquotSampleLabel]

      Header: AliquotSampleLabel
      Class: String

    AliquotProtocols

    Protocols used to create AliquotSamples prior to starting the experiment.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    AliquotPreparationProtocols

    Protocols used to mix, centrifuge, incubate, and filter the AliquotSamples prior to starting the experiment.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    AliquotSamples

    Samples corresponding to aliquots of SamplesIn generated during sample preparation and intended for use in this experiment.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link
    Relation: Object[Sample]

    AliquotContainers

    Containers that hold AliquotSamples generated during sample preparation and intended for use in this experiment.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    SaveAliquots

    Indicates if the AliquotSamples should be stored after the experiment, rather than being discarded.
    Format: Single
    Class: Expression
    Programmatic Pattern: BooleanP

    ConsolidateAliquots

    Indicates if identical aliquots should be consolidated in a single sample.
    Format: Single
    Class: Expression
    Programmatic Pattern: BooleanP

    AliquotPreparation

    Indicates if the aliquotting should occur manually or on a robotic liquid handler.
    Format: Single
    Class: Expression
    Programmatic Pattern: PreparationMethodP

    AliquotVolumes

    For each member of SamplesIn, the volume transferred from the sample into the aliquot sample which is used in lieu of the initial sample for the experiment.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterP[0 Micro Liter]

    AliquotMasses

    For each member of SamplesIn, the mass of a solid transferred from the sample into the aliquot sample which is used in lieu of the initial sample for the experiment.
    Format: Multiple
    Class: Real
    Unit: 1 milligram
    Programmatic Pattern: GreaterP[0 Milligram]

    AliquotAmounts

    For each member of SamplesIn, the amount transferred from the sample into the aliquot sample which is used in lieu of the initial sample for the experiment.
    Format: Multiple
    Class: VariableUnit
    Programmatic Pattern: GreaterP[0 Milliliter] | GreaterP[0 Milligram] | GreaterP[0 Unit, 1 Unit]

    TargetConcentrations

    For each member of SamplesIn, the final concentration of analyte in the aliquot sample which is used in lieu of the initial sample for the experiment.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: Milligram Hold[GreaterP[0 Micro Molar] | GreaterP[0 ----------]] Milliliter

    AssayVolumes

    For each member of SamplesIn (or PooledSamplesIn), the total volume of the reaction mixture which is used in lieu of the initial sample for the experiment.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Micro Liter]

    AssayBuffers

    For each member of SamplesIn (or PooledSamplesIn), the final buffers used to generate AliquotSamples by aliquoting SamplesIn.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    ConcentratedBuffers

    For each member of SamplesIn (or PooledSamplesIn), the concentrated buffer source which is added to the AliquotSamples to obtain 1x buffer concentration after dilution of the AliquotSamples which are used in lieu of the SamplesIn for the experiment.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    BufferDilutionFactors

    For each member of SamplesIn (or PooledSamplesIn), he dilution factor by which the concentrated buffer is diluted in preparing the AliquotSamples to obtain a 1x buffer concentration after dilution of the AliquotSamples which are used in lieu of the SamplesIn for the experiment.
    Format: Multiple
    Class: Real
    Programmatic Pattern: GreaterP[0]

    BufferDiluents

    For each member of SamplesIn (or PooledSamplesIn), the diluent used to dilute the concentration of the concentrated buffer in preparing the AliquotSamples which are used in lieu of the SamplesIn for the experiment.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    ConcentratedBuffer

    The concentrated buffer source which is added to each of the AliquotSamples to obtain 1x buffer concentration after dilution of the AliquotSamples which are used in lieu of the SamplesIn for the experiment.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    BufferDilutionFactor

    The dilution factor by which the concentrated buffer is diluted in preparing the AliquotSamples to obtain a 1x buffer concentration after dilution of the AliquotSamples which are used in lieu of the SamplesIn for the experiment.
    Format: Single
    Class: Integer
    Programmatic Pattern: GreaterP[0]

    BufferDiluent

    The diluent used to dilute the concentration of the concentrated buffer in preparing the AliquotSamples which are used in lieu of the SamplesIn for the experiment.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    AssayBuffer

    The desired buffer for the AliquotSamples which are used in lieu of the SamplesIn for the experiment.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

Sample Post-Processing

    PostProcessingProtocols

    Protocols used to perform post-processing such as sample imaging or volume measurement.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    ImageSample

    Indicates if the samples that are modified in the course of the experiment are imaged after running the experiment.
    Format: Single
    Class: Expression
    Programmatic Pattern: BooleanP

    MeasureVolume

    Indicates if the volume of the liquid samples modified in the course of the experiment are measured after running the experiment.
    Format: Single
    Class: Expression
    Programmatic Pattern: BooleanP

    MeasureWeight

    Indicates if the weight of the solid samples modified in the course of the experiment are measured after running the experiment.
    Format: Single
    Class: Expression
    Programmatic Pattern: BooleanP

    Measure

    Indicates if the volume/weight of the samples modified in the course of the experiment are measured after running the experiment.
    Format: Single
    Class: Expression
    Programmatic Pattern: BooleanP

    Storage

    Indicates the conditions under which any samples generated by this experiment are stored after the protocol is completed.
    Format: Single
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

Experimental Results

    Data

    Any primary data generated by this protocol.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    SamplesOut

    Any preparative samples generated by the protocol.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    ContainersOut

    Any containers holding SamplesOut generated by this protocol.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    EnvironmentalData

    Measurements of environmental conditions (temperature and humidity) recorded during the execution of this protocol.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    DataFile

    The output data file generated at the conclusion of the experiment by the instrument.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

Troubleshooting

    TroubleshootingReports

    Reports for errors that require troubleshooting associated with the execution of this top-level protocol.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

Resources

    AwaitingResources

    Indicates if this protocol is awaiting the arrival of items before it can be begun or continued.
    Format: Single
    Class: Boolean
    Programmatic Pattern: BooleanP

    ShippingMaterials

    Indicates the transactions, and the specific products or samples therein, that must be received before this protocol can be begun or continued.
    Format: Multiple

    [[1]] Transaction

    [[2]] Required Product

    HazardousWaste

    The types of waste generated by this protocol.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    DispenserContainers

    Containers gathered as destinations for any resources obtained from a chemical dispenser.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    GasSources

    A list of containers that supplied gas to instruments in this protocol through plumbing connections.
    Format: Multiple

    [[1]] Gas Type

      Header: Gas Type
      Class: Expression
      Programmatic Pattern: GasP

    [[2]] Source Container

      Header: Source Container
      Class: Link
      Programmatic Pattern: _Link

    [[3]] Supplied Instrument

      Header: Supplied Instrument
      Class: Link
      Programmatic Pattern: _Link

Cleaning

    WasteGenerated

    For each type of waste generated by this protocol, the total amount (in grams) generated during the conduct of the protocol.
    Format: Multiple

    [Waste]

    [Weight]

      Header: Weight
      Class: Real
      Unit: 1 gram

Storage Information

    StoragePrice

    The total monthly price for warehousing all user owned items associated with this protocol in an ECL facility under the storage conditions specified by each item.
    Format: Single
    Class: Real
    Unit: 1 US dollar per month
    Programmatic Pattern: USD Hold[GreaterEqualP[0 -----]] Month

    CartridgeStorageCondition

    The non-default storage condition for the Cartridge after the protocol is completed.
    Format: Single
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

Sample Storage

    SamplesInStorage

    For each member of SamplesIn, The storage conditions under which any input samples to this experiment should be stored after their usage in this experiment.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    AliquotStorage

    For each member of AliquotSamples, The storage conditions under which any aliquot samples generated by this experiment should be stored after the protocol is completed.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    SamplesOutStorage

    For each member of SamplesOut, the storage conditions under which any output samples generated by this experiment should be stored after the protocol is completed.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

Option Handling

    ResolvedOptions

    The final options used as parameters for this protocol, after automatic options are resolved.
    Format: Single
    Class: Compressed
    Programmatic Pattern: {_Rule...}

    UnresolvedOptions

    The verbatim options originally input by the protocol author to generate this protocol, often with some options set to Automatic.
    Format: Single
    Class: Compressed
    Programmatic Pattern: {_Rule...}

Computations

    ParallelComputations

    List of computational jobs generated and run in parallel to the execution of this protocol.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    ComputationsOutstanding

    Indicates if any of the computation jobs in ParallelComputations have not yet completed.
    Format: Single
    Class: Boolean
    Programmatic Pattern: BooleanP

    ErroneousComputations

    List of computational jobs generated and run in parallel to the execution of this protocol in which a warning or error was thown, or that did not finish.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

Instrument Setup

    Cartridge

    The capillary electrophoresis cartridge loaded on the instrument for Capillary gel Electrophoresis-SDS experiments. The cartridge holds a single capillary and the anode running buffer.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    CartridgeInsert

    The insert loaded on the Capillary gel Electrophoresis-SDS cartridge. The insert holds the top running buffer or the cleaning cartridge.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    CartridgeInsertReplacement

    The insert to be picked if needed, based on ReplaceCartridgeInsert.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link | Null

    TopRunningBuffer

    Indicates the buffer loaded onto the cartridge for separation. This buffer must be compatible with the cathode running buffer loaded on the instrument (see: OnBoardRunningBuffer).
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    TopRunningBufferBackup

    Indicates the buffer loaded onto the cartridge for separation. This is a backup that will be picked only if a cartridge purge is required.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    PurgeCartridge

    Indicates whether cartridge should be purged even if not prompted by instrument.
    Format: Single
    Class: Expression
    Programmatic Pattern: IfRequired | True | False

    CartridgeTipCleanup

    A beaker with water used to clean the capillary tip if needed after a run ends.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    SampleTemperature

    The sample tray temperature at which samples are maintained while awaiting injection.
    Format: Single
    Class: Integer
    Unit: 1 degree Celsius
    Programmatic Pattern: GreaterP[0 Kelvin]

    Caps

    The caps used to seal reagent vials during a gel electrophoresis SDS experiment.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    ContainersWithPressureCaps

    Containers that are currently capped with pressure caps.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    ContainersWithClearCaps

    Containers that are currently capped with clear caps.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    CleanupCartridgeCap

    The caps used to seal reagent vials during a gel electrophoresis SDS experiment.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    ConditioningAcid

    The Conditioning Acid solution used to wash the capillary (every 12 injections).
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    ConditioningBase

    The Conditioning Base solution used to wash the capillary (every 12 injections).
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    ConditioningWashSolution

    The solution used to wash the capillary after acid and base wash (every 12 injections).
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    SeparationMatrix

    The sieving matrix loaded onto the capillary before each sample for separation. The mash-like matrix slows the migration of proteins based on their size so that larger proteins migrate slower than smaller ones.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    SystemWashSolution

    The solution used to wash the capillary after conditioning and, separately, rinse the tip twice before every injection.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    PlaceholderContainer

    The PlaceholderContainer is an empty vial used to dry the capillary after each wash.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    BottomRunningBuffer

    Indicates the buffer in which the capillary docks for separation. This buffer must be compatible with the anode running buffer loaded on the Capillary gel electrophoresis SDS cartridge (see: OnBoardRunningBuffer).
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    ConditioningAcidStorage Condition

    The non-default storage condition for the ConditioningAcid once the experiment is set up.
    Format: Single
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    ConditioningBaseStorage Condition

    The non-default storage condition for the ConditioningBase once the experiment is set up.
    Format: Single
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    SeparationMatrixStorage Condition

    The non-default storage condition for the SeparationMatrix once the experiment is set up.
    Format: Single
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    SystemWashSolutionStorage Condition

    The non-default storage condition for the SystemWashSolution once the experiment is set up.
    Format: Single
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    PlateSeal

    The adhesive film used to seal the assay plate once it is prepared for injection. The seal should be pierceable, if not, it should be removed before loading the plate to the instrument.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

Cartridge Cleanup

    CleanupCartridge

    Indicates the item that is used to clean up the experiment cartridge after every run.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

    CleanupCartridgeWashSolution

    Indicates the solution that is used to clean up the experiment cartridge after every run and its appropriate cap.
    Format: Single
    Class: Link
    Programmatic Pattern: _Link

Separation

    InjectionVoltageDuration Profiles

    For each member of SamplesIn, indicates the series of voltages and durations to apply onto the capillary while docked in the sample to electroinject proteins in the sample into the matrix in the capillary.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: {{GreaterEqualP[0 Volt], GreaterP[0 Second]}..}

    SeparationVoltageDuration Profiles

    For each member of SamplesIn, indicates the series of voltages and durations to apply onto the capillary while docked in running buffer to separate proteins by molecular weight as they migrate through the separation matrix in the capillary.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: {{GreaterEqualP[0 Volt], GreaterP[0 Minute]}..}

Ladders

    Ladders

    A mixtures of known analytes that serve as reference for interpolation of the molecular weight of unknown samples in the experiment.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    LadderStorageConditions

    For each member of Ladders, indicates the non-default storage condition.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    LadderAnalytes

    For each member of Ladders, Indicates the Molecules in the ladder mixture.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: {ObjectP[Model[Molecule]]..}

    LadderAnalyteMolecularWeights

    For each member of Ladders, indicates the molecular weights of analytes included in ladder.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: {GreaterP[0 Kilodalton]..}

    LadderAnalyteLabels

    For each member of Ladders, indicates the label of each analyte included in ladder.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: {_String..}

    LadderTotalVolumes

    For each member of Ladders, indicates the final volume in the assay tube prior to loading onto AssayContainer. Each tube contains a ladder, an InternalReference, and an SDSBuffer.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    LadderDilutionFactors

    For each member of Ladders, indicates the factor by which the ladder should be diluted by to reach working concentration.
    Format: Multiple
    Class: Real
    Programmatic Pattern: GreaterP[1]

    LadderVolumes

    For each member of Ladders, indicates the volume of ladder required to reach its working concentration in LadderTotalVolume.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    LadderPremadeMasterMix Reagents

    For each member of Ladders, indicates the premade master mix used for CESDS experiment, containing an SDS buffer, an internal standard, and reducing and / or alkylating agents (if applicable).
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    LadderPremadeMasterMix Diluents

    For each member of Ladders,indicates the solution used to dilute the premade master mix used to its working concentration.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    LadderPremadeMasterMixReagent DilutionFactors

    For each member of Ladders, indicates the factor by which the premade mastermix should be diluted by in the final assay tube.
    Format: Multiple
    Class: Real
    Programmatic Pattern: GreaterEqualP[1]

    LadderPremadeMasterMixVolumes

    For each member of Ladders, indicates the volume of the premade mastermix required to reach its final concentration.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    LadderInternalReferences

    For each member of Ladders, indicates the internal standard stock solution added in sample preparation. The internal standard stock solution contains the analyte that serves as the reference by which Relative Migration Time is normalized. By default a 10 KDa marker is used.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    LadderInternalReference DilutionFactors

    For each member of Ladders, indicates the factor by which the InternalReference needs to be diluted to reach working concentration.
    Format: Multiple
    Class: Real
    Programmatic Pattern: GreaterEqualP[1]

    LadderInternalReference Volumes

    For each member of Ladders, indicates the volume of InternalReference to be diluted by a factor equal to InternalReferenceDilutionFactor to reach working concentration in the final assay volume containing all other components (i.e., Ladder SDS buffer, and reducing/alkylating agents).
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    LadderConcentratedSDSBuffers

    For each member of Ladders, indicates the SDS Buffer concentrate used to dilute and denature the sample.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    LadderConcentratedSDSBuffer DilutionFactors

    For each member of Ladders, indicates the factor by which the ConcentratedSDSBuffer needs to be diluted to reach working concentration.
    Format: Multiple
    Class: Real
    Programmatic Pattern: GreaterEqualP[1]

    LadderConcentratedSDSBuffer Volumes

    For each member of Ladders, indicates the volume of ConcentratedSDSBuffer to reach its working concentration in the final assay volume containing all other components (i.e., Ladder internal standard, and reducing/alkylating agents).
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    LadderDiluents

    For each member of Ladders, indicates the solution used to bring the assay tube to TotalVolume so that all components are at working concentration in the final assay volume containing all other components (i.e., Ladder internal standard, SDS buffer, and reducing/alkylating agents).
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    LadderSDSBuffers

    For each member of Ladders, indicates the SDS Buffer used to dilute and denature the sample.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    LadderSDSBufferVolumes

    For each member of Ladders, indicates the volume of SDSBuffer to add to Ladder to reach working concentration in the final assay volume containing all other components (i.e., Ladder internal standard, and reducing/alkylating agents).
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    LadderReducingAgents

    For each member of Ladders, indicates the reducing agent, e.g., β-mercaptoethanol or Dithiothreitol, added to the Ladder to reduce disulfide bridges in proteins.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    LadderReducingAgentTarget Concentrations

    For each member of Ladders, indicates the final concentration of the ReducingAgent in the sample.
    Format: Multiple
    Class: VariableUnit
    Programmatic Pattern: GreaterEqualP[0 Molar] | RangeP[0 VolumePercent, 100 VolumePercent]

    LadderReducingAgentVolumes

    For each member of Ladders, indicates the volume of the ReducingAgent added to the Ladder to reach working concentration in the final assay volume containing all other components (i.e., Ladder internal standard, SDSBuffer and alkylating agents).
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    LadderAlkylatingAgents

    For each member of Ladders, indicates the alkylating agent, e.g., Iodoacetamide, added to the Ladder to prevent protein fragmentation.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    LadderAlkylatingAgentTarget Concentrations

    For each member of Ladders, indicates the final concentration of the AlkylatingAgent in the sample.
    Format: Multiple
    Class: Real
    Unit: 1 millimolar
    Programmatic Pattern: GreaterEqualP[0 Molar]

    LadderAlkylatingAgentVolumes

    For each member of Ladders, indicates the volume of the AlkylatingAgent added the sample.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    LadderSedimentation SupernatantVolumes

    For each member of Ladders, indicates the volume of supernatant that should be aliquoted to assay AssayContainer after denaturation and centrifugation.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    LadderInternalReference StorageConditions

    For each member of Ladders, indicates the non-default storage condition for the InternalReference after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    LadderConcentratedSDSBuffer StorageConditions

    For each member of Ladders, indicates the non-default storage condition for the ConcentratedSDSBuffer after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    LadderDiluentStorage Conditions

    For each member of Ladders, indicates the non-default storage condition for the Diluent after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    LadderSDSBufferStorage Conditions

    For each member of Ladders, indicates the non-default storage condition for the SDSBuffer after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    LadderReducingAgentStorage Conditions

    For each member of Ladders, indicates the non-default storage condition for the ReducingAgent after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    LadderAlkylatingAgentStorage Conditions

    For each member of Ladders, indicates the non-default storage condition for the AlkylatingAgent after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    LadderInjectionVoltage DurationProfiles

    For each member of Ladders, indicates the series of voltages and durations to apply onto the capillary while sampling Ladders for separation.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: {{GreaterEqualP[0 Volt], GreaterP[0 Second]}..}

    LadderSeparationVoltage DurationProfiles

    For each member of Ladders, indicates the series of voltages and durations to apply onto the capillary while docked in running buffer to separate proteins by molecular weight as they migrate through the separation matrix in the capillary.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: {{GreaterEqualP[0 Volt], GreaterP[0 Minute]}..}

Standards

    Standards

    Known analytes that serve as standards for the experiment.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    StandardStorageConditions

    For each member of Standards, indicates the non-default storage condition.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    StandardTotalVolumes

    For each member of Standards, indicates the final volume in the assay tube prior to loading onto AssayContainer. Each tube contains Standard InternalReference, SDSBuffer, and ReducingAgent and/or AlkylatingAgent.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    StandardVolumes

    For each member of Standards, indicates the volume of blank required.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    StandardPremadeMasterMix Reagents

    For each member of Standards, indicates the premade master mix used for CESDS experiment, containing an SDS buffer, an internal standard, and reducing and / or alkylating agents (if applicable).
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    StandardPremadeMasterMix Diluents

    For each member of Standards,indicates the solution used to dilute the premade master mix used to its working concentration.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    StandardPremadeMasterMix ReagentDilutionFactors

    For each member of Standards, indicates the factor by which the premade mastermix should be diluted by in the final assay tube.
    Format: Multiple
    Class: Real
    Programmatic Pattern: GreaterEqualP[1]

    StandardPremadeMasterMix Volumes

    For each member of Standards, indicates the volume of the premade mastermix required to reach its final concentration.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    StandardInternalReferences

    For each member of Standards, indicates the internal standard stock solution added in sample preparation. The internal standard stock solution contains the analyte that serves as the reference by which Relative Migration Time is normalized. By default a 10 KDa marker is used.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    StandardInternalReference DilutionFactors

    For each member of Standards, indicates the factor by which the InternalReference needs to be diluted to reach working concentration.
    Format: Multiple
    Class: Real
    Programmatic Pattern: GreaterEqualP[1]

    StandardInternalReference Volumes

    For each member of Standards, indicates the volume of InternalReference to be diluted by a factor equal to InternalReferenceDilutionFactor to reach working concentration in the final assay volume containing all other components (i.e., Standard SDS buffer, and reducing/alkylating agents).
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    StandardConcentratedSDS Buffers

    For each member of Standards, indicates the SDS Buffer concentrate used to dilute and denature the sample.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    StandardConcentratedSDSBuffer DilutionFactors

    For each member of Standards, indicates the factor by which the ConcentratedSDSBuffer needs to be diluted to reach working concentration.
    Format: Multiple
    Class: Real
    Programmatic Pattern: GreaterEqualP[1]

    StandardConcentratedSDSBuffer Volumes

    For each member of Standards, indicates the volume of ConcentratedSDSBuffer to reach its working concentration in the final assay volume containing all other components (i.e., Standard internal standard, and reducing/alkylating agents).
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    StandardDiluents

    For each member of Standards, indicates the solution used to bring the assay tube to TotalVolume so that all components are at working concentration in the final assay volume containing all other components (i.e., Standard internal standard, SDS buffer, and reducing/alkylating agents).
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    StandardSDSBuffers

    For each member of Standards, indicates the SDS Buffer used to dilute and denature the sample.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    StandardSDSBufferVolumes

    For each member of Standards, indicates the volume of SDSBuffer to add to Standard to reach working concentration in the final assay volume containing all other components (i.e., Standard internal standard, and reducing/alkylating agents).
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    StandardReducingAgents

    For each member of Standards, indicates the reducing agent, e.g., β-mercaptoethanol or Dithiothreitol, added to the Standard to reduce disulfide bridges in proteins.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    StandardReducingAgentTarget Concentrations

    For each member of Standards, indicates the final concentration of the ReducingAgent in the sample.
    Format: Multiple
    Class: VariableUnit
    Programmatic Pattern: GreaterEqualP[0 Molar] | RangeP[0 VolumePercent, 100 VolumePercent]

    StandardReducingAgentVolumes

    For each member of Standards, indicates the volume of the ReducingAgent added to the Standard to reach working concentration in the final assay volume containing all other components (i.e., Standard internal standard, SDSBuffer and alkylating agents).
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    StandardAlkylatingAgents

    For each member of Standards, indicates the alkylating agent, e.g., Iodoacetamide, added to the Standard to prevent protein fragmentation.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    StandardAlkylatingAgentTarget Concentrations

    For each member of Standards, indicates the final concentration of the AlkylatingAgent in the sample.
    Format: Multiple
    Class: Real
    Unit: 1 millimolar
    Programmatic Pattern: GreaterEqualP[0 Molar]

    StandardAlkylatingAgent Volumes

    For each member of Standards, indicates the volume of the AlkylatingAgent added the sample.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    StandardSedimentation SupernatantVolumes

    For each member of Standards, indicates the volume of supernatant that should be aliquoted to assay AssayContainer after denaturation and centrifugation.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    StandardInternalReference StorageConditions

    For each member of Standards, indicates the non-default storage condition for the InternalReference after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    StandardConcentratedSDSBuffer StorageConditions

    For each member of Standards, indicates the non-default storage condition for the ConcentratedSDSBuffer after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    StandardDiluentStorage Conditions

    For each member of Standards, indicates the non-default storage condition for the Diluent after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    StandardSDSBufferStorage Conditions

    For each member of Standards, indicates the non-default storage condition for the SDSBuffer after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    StandardReducingAgentStorage Conditions

    For each member of Standards, indicates the non-default storage condition for the ReducingAgent after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    StandardAlkylatingAgent StorageConditions

    For each member of Standards, indicates the non-default storage condition for the AlkylatingAgent after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    StandardInjectionVoltage DurationProfiles

    For each member of Standards, indicates the series of voltages and durations to apply onto the capillary while sampling Standards for separation.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: {{GreaterEqualP[0 Volt], GreaterP[0 Second]}..}

    StandardSeparationVoltage DurationProfiles

    For each member of Standards, indicates the series of voltages and durations to apply onto the capillary while docked in running buffer to separate proteins by molecular weight as they migrate through the separation matrix in the capillary.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: {{GreaterEqualP[0 Volt], GreaterP[0 Minute]}..}

Blanks

    Blanks

    Known analytes that serve as Blanks for the experiment.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    BlankStorageConditions

    For each member of Blanks, indicates the non-default storage condition.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    BlankTotalVolumes

    For each member of Blanks, indicates the final volume in the assay tube prior to loading onto AssayContainer. Each tube contains Blank, InternalReference, SDSBuffer, and ReducingAgent and/or AlkylatingAgent.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    BlankVolumes

    For each member of Blanks, indicates the volume of blank required.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    BlankPremadeMasterMixReagents

    For each member of Blanks, indicates the premade master mix used for CESDS experiment, containing an SDS buffer, an internal Blank, and reducing and / or alkylating agents (if applicable).
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    BlankPremadeMasterMixDiluents

    For each member of Blanks,indicates the solution used to dilute the premade master mix used to its working concentration.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    BlankPremadeMasterMixReagent DilutionFactors

    For each member of Blanks, indicates the factor by which the premade mastermix should be diluted by in the final assay tube.
    Format: Multiple
    Class: Real
    Programmatic Pattern: GreaterEqualP[1]

    BlankPremadeMasterMixVolumes

    For each member of Blanks, indicates the volume of the premade mastermix required to reach its final concentration.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    BlankInternalReferences

    For each member of Blanks, indicates the internal Blank stock solution added in sample preparation. The internal Blank stock solution contains the analyte that serves as the reference by which Relative Migration Time is normalized. By default a 10 KDa marker is used.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    BlankInternalReference DilutionFactors

    For each member of Blanks, indicates the factor by which the InternalReference needs to be diluted to reach working concentration.
    Format: Multiple
    Class: Real
    Programmatic Pattern: GreaterEqualP[1]

    BlankInternalReferenceVolumes

    For each member of Blanks, indicates the volume of InternalReference to be diluted by a factor equal to InternalReferenceDilutionFactor to reach working concentration in the final assay volume containing all other components (i.e., Blank SDS buffer, and reducing/alkylating agents).
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    BlankConcentratedSDSBuffers

    For each member of Blanks, indicates the SDS Buffer concentrate used to dilute and denature the sample.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    BlankConcentratedSDSBuffer DilutionFactors

    For each member of Blanks, indicates the factor by which the ConcentratedSDSBuffer needs to be diluted to reach working concentration.
    Format: Multiple
    Class: Real
    Programmatic Pattern: GreaterEqualP[1]

    BlankConcentratedSDSBuffer Volumes

    For each member of Blanks, indicates the volume of ConcentratedSDSBuffer to reach its working concentration in the final assay volume containing all other components (i.e., Blank internal Blank, and reducing/alkylating agents).
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    BlankDiluents

    For each member of Blanks, indicates the solution used to bring the assay tube to TotalVolume so that all components are at working concentration in the final assay volume containing all other components (i.e., Blank internal Blank, SDS buffer, and reducing/alkylating agents).
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    BlankSDSBuffers

    For each member of Blanks, indicates the SDS Buffer used to dilute and denature the sample.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    BlankSDSBufferVolumes

    For each member of Blanks, indicates the volume of SDSBuffer to add to Blank to reach working concentration in the final assay volume containing all other components (i.e., Blank internal Blank, and reducing/alkylating agents).
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    BlankReducingAgents

    For each member of Blanks, indicates the reducing agent, e.g., β-mercaptoethanol or Dithiothreitol, added to the Blank to reduce disulfide bridges in proteins.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    BlankReducingAgentTarget Concentrations

    For each member of Blanks, indicates the final concentration of the ReducingAgent in the sample.
    Format: Multiple
    Class: VariableUnit
    Programmatic Pattern: GreaterEqualP[0 Molar] | RangeP[0 VolumePercent, 100 VolumePercent]

    BlankReducingAgentVolumes

    For each member of Blanks, indicates the volume of the ReducingAgent added to the Blank to reach working concentration in the final assay volume containing all other components (i.e., Blank internal Blank, SDSBuffer and alkylating agents).
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    BlankAlkylatingAgents

    For each member of Blanks, indicates the alkylating agent, e.g., Iodoacetamide, added to the Blank to prevent protein fragmentation.
    Format: Multiple
    Class: Link
    Programmatic Pattern: _Link

    BlankAlkylatingAgentTarget Concentrations

    For each member of Blanks, indicates the final concentration of the AlkylatingAgent in the sample.
    Format: Multiple
    Class: Real
    Unit: 1 millimolar
    Programmatic Pattern: GreaterEqualP[0 Molar]

    BlankAlkylatingAgentVolumes

    For each member of Blanks, indicates the volume of the AlkylatingAgent added the sample.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    BlankSedimentationSupernatant Volumes

    For each member of Blanks, indicates the volume of supernatant that should be aliquoted to assay AssayContainer after denaturation and centrifugation.
    Format: Multiple
    Class: Real
    Unit: 1 microliter
    Programmatic Pattern: GreaterEqualP[0 Microliter]

    BlankInternalReferenceStorage Conditions

    For each member of Blanks, indicates the non-default storage condition for the InternalReference after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    BlankConcentratedSDSBuffer StorageConditions

    For each member of Blanks, indicates the non-default storage condition for the ConcentratedSDSBuffer after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    BlankDiluentStorageConditions

    For each member of Blanks, indicates the non-default storage condition for the Diluent after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    BlankSDSBufferStorage Conditions

    For each member of Blanks, indicates the non-default storage condition for the SDSBuffer after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    BlankReducingAgentStorage Conditions

    For each member of Blanks, indicates the non-default storage condition for the ReducingAgent after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    BlankAlkylatingAgentStorage Conditions

    For each member of Blanks, indicates the non-default storage condition for the AlkylatingAgent after samples are transferred to assay tubes.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: SampleStorageTypeP | Disposal

    BlankInjectionVoltageDuration Profiles

    For each member of Blanks, indicates the series of voltages and durations to apply onto the capillary while sampling Blanks for separation.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: {{GreaterEqualP[0 Volt], GreaterP[0 Second]}..}

    BlankSeparationVoltage DurationProfiles

    For each member of Blanks, indicates the series of voltages and durations to apply onto the capillary while docked in running buffer to separate proteins by molecular weight as they migrate through the separation matrix in the capillary.
    Format: Multiple
    Class: Expression
    Programmatic Pattern: {{GreaterEqualP[0 Volt], GreaterP[0 Minute]}..}
Last modified on Mon 26 Sep 2022 15:43:49